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Identifikasi struktur senyawa berpotensi ant-kanker ginjal yang selektif dari daun Nerium indicum Mill (Structure identification of potential compound as selective renal anticancer isolated from Nerium indicum Mill, leaves

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Oleandrin in one of cardenolida compound isolated from and active fraction of Nerium indicum Mill leaves. (fam. Apocynaseae), which have cytotxic effect on several human cancer cells, and also to normal cells in vitro. Another compound which was potential as renal anticancer has also been isolated from N. indicum. However, its chemical structure has not been discovered. The aim of this study was to identify the potential compound as selective to renal cancer present in the leaves of N. indicum.
The potential compound was isolated from the active fraction using preparative TLC and structure education was done was by using spectroscopic methods (UV, IR, MS and NMR)
Base on this spectra and by comparison with oleandrin data, it was indicated that the potential compound as Renal anticancer was as 16,17 dehydrodeacetyl-5ά-oleandrin.

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Series Title

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Call Number

Majalah Farmasi Indonesia: Vol. 19 (2) 2008: 57-64

Publisher

Yogyakarta : Fakultas Farmasi UGM, Badan Litbangkes., 2008

Collation

8 p.

Language

ISBN/ISSN

0126-1037

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Edition

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Subject(s)

plants, medicinal
ANTIFUNGAL AGENTS.
CANDIDA ALBICANS

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