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Relaksasi Otot Polos Pembuluh Darah Akibat Pengaruh Nitric Oxide (NO) (Vascular Smooth Muscle Relaxation by Nitric Oxide (NO)

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Nitric oxide (NO) was once regarded as a noxious environmental pollutant, when in the 1980s several lines of research showed that NO is essential of the human body. NO is a short-lived gas that is produced locally from L-arginine by the enzyme NO-synthase NOS). NOS is found in preganglionic and postganglionic autonomic neurons, as well as in vascular endothelial cells. Inside the VSMC (vascular smooth muscle cells) is the receptor for No, a soluble guanylyl cyclase (sGC) that converts GTP to cGMP. cGMP activate cGKI, cGKI cause decrease on the cytosolic calcium concentration [Ca²+], and then reduce MLCK activity, so relaxation occurs.

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Ketersediaan

Informasi Detail

Judul Seri

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No. Panggil

Majalah Ilmu Faal Indonesi,7(3):211-219

Penerbit

Surabaya : Ikatan Ahli Ilmu Faal Indonesia., 2008

Deskripsi Fisik

5P.

Bahasa

ISBN/ISSN

0215-1995

Klasifikasi

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Tipe Isi

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Tipe Media

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Tipe Pembawa

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Edisi

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Subjek

MUSCLE, SMOOTH, VASCULAR
NITRIC OXIDE

Info Detail Spesifik

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Pernyataan Tanggungjawab

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Versi lain/terkait

Lampiran Berkas

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