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Karakterisasi Daun Miana (Plectranthus scutellarioides (L.) Bth) dan Buah Sirih (Piper betle L.) Secara Fisiko Kimia dari Ramuan Lokal Antimalaria Daerah Slawesi Utara

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Multidrug-resistant Plasmodium falciparum strains are an increasing problem in endemic areas and
are partly responsible for the worsening malaria situation around the world. New cheap and effective
compounds active in combination with available drug in the field, such as indegenous traditional
medicine, are urgently needed. The aim of this work was to characterize the simplitia and extracts of an
indegenous traditional medicine which usually used in North Sulawesi. Since this indigenous traditional
medicine has been largely used and well-tolerated in humans, secondary metabolites derivatives of the
plants could be in the near future associated with already available drugs in order to delay the spread
of P. falciparum resistance. Non polar, semi polar and polar extracts of P. scutellarioides folium and P.
betle fruit are prepared of each plants part obtained, then evaluated by using chromatography and
densitometry methods following identification.
Keywords: P. falciparum, antimalarial activity, P. scutellarioides folium, P. betle
fruit, secondary metabolites

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Series Title

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Call Number

Media Litbang Kesehatan,18(4)2008:213-225

Publisher

Jakarta : Badan Litbang Kesehatan., 2008

Collation

7p.

Language

ISBN/ISSN

1410-2935

Classification

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Content Type

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Media Type

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Carrier Type

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Edition

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Subject(s)

PLANTS MEDICIANAL

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