Text

Interaksi Obat dan Beberapa Implikasinya

---

Drug-drug interactions can initiate undesirable or adverse effects. This could have a clinical
implication and could also become serious health problems. Since a large number of drugs are
introduced and marketed every year, new interactions between concomitant medications might possibly
increase. The safety profile of drugs including the impacts of drug-drug interactions can be provided
from pharmacoepidemiology and pharmacovigilonce data. There are some mechanisms of drug-dug interactions, i.e. pharmaceutics interaction, pharmacokinetics and pharmacodynamics interactions. However, only harmacodynamic interaction can be predicted and the effect usually applies equally to any drugs in the same class therapy. On the other hand, pharmacokinetic interactions cannot be predicted or extrapolated to any drugs in the same class
therapy because of differences in their pharmacokinetics profiles. Information on how is the mechanism
of drug-drug interaction is needed, so the possible adverse effect due to drug-drug interactions can be
anticipated.
Keywords: drug-drug interaction, adverse effect, pharmacokinetics, pharmacodynamics

---

Availability

No copy data

Detail Information

Series Title

-

Call Number

Media Litbang Kesehatan,18(4):175-184

Publisher

Jakarta : Badan Litbang Kesehatan., 2008

Collation

5P.

Language

ISBN/ISSN

1410-2935

Classification

-

Content Type

-

Media Type

-

Carrier Type

-

Edition

-

Subject(s)

PHARMACOKINETICS
DRUG INTERACTION
ADVERSE EFFECTS

Specific Detail Info

-

Statement of Responsibility

-

Other version/related

File Attachment

Comments

---

You must be logged in to post a comment