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Herpes Simplex Virus Infection the Roles of T-Lymphocytes in Host Responses
T-lymphoxytes are the most important component of the immune response to control recurent infections. T-lumphocutes of CD4+ and CD8+ bearing T-cells can kill HSV intected host cells. The relation between apecific T-cells responses and severity of HSV disease of HSV disease have not been consistently detcted. Interaction between T-cells responses and HSV and host immunity. Reactivation can result in recurences with the implication of transmission and/or disease. Loecular definition of T-cell responses for HSV may lead to immunological intervention to prevent HSV disease. Impaired T-cell immunity should be considered as a risk factor for severe infections.
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