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Chemotherapy on Cervical Cancer (Kemoterapi pada Kanker Serviks)

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Objective: To discuss the role of chemotherapy in the management of cervical cancer. Design/Data identification: Literature study. Results: In order to enhance the results of the treatment of cervical cancer, in addition to operation or radiation, it is necessary to have other alternative. i.e. chemotherapy given for both recurrent cases/metastasis and as part of first treatment, such as neoadjuvant (pre-radiation/pre-operation), chemoradiation (simultaneous). or adjuvant. The affective chemotherapy drugs is cisplatin of cisplatin with other drugs in terms of survival. The administration of chemotherapy (cisplatin in the recurrent patients) for distant metastasis induces a response, but only for a period of a few months, and chemotherapy is particularly effective for metastasis outside of pelvis (for example, in lung), even to the extent that chemotherapy may cure it. Preradiation neoadjuvant chemotherapy should not be given because as radiosynthesizer and can improve pelvic control and survival. Adjuvant chemotherapy, particularly after radical hysteroctomy with risk factors, is also beneficial in improving both pelvic control and distant metastasis. Conclusions: The role of chemotherapy in the management of cervical cancer is still limited. Single chemotherapy treatment (cisplatin) is, in fact, not inferior to the combined chemotherapy in terms of survival.

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Majalah Obstetri dan Ginekologi Indonesia,20(3)199

Publisher

: ., 1996

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Subject(s)

cervix neoplasms
drugs therapy

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