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Lipid Serum Profiles in Controlled Non Insuline Dependent Diabetes Mellitus Patients (Profil Lipid Serum pada Penderita Diabetes Melitus tidak Tergantung Insulin yang Sudah Terkendali)

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It is estimated more than 50 percent of diabetic patients are dyslipidemic, this prevalence is higher in those with poorly controlled diabetic. Glycemic control may improve the lipid serum profiles, eventhough glycemic control may improve the lipid serum profiles, eventhough glycemic control by it self is not sufficient to control diabetic dyslipidemia. There is very little publications to control diabetic dyslipidemia in Indonesia literatures. The purpose of this study is to evaluate the serum lipid profiles in good controlled NIDDM patients. The patients were recruited from the outpatient department of Academic Hospital Jaury and private clinic. Blood samples were taken in the early morning after 12 hours fasting. The serum were examined for total cholesterol, triglyceride and HDL-cholesterol. Normal value for total cholesterol more than or equal to 200 mg/dl, triglyceride less than or equal to 200 mg/dl and HDL-cholesterol more than or equal to 35 mg/dl. HbA1 was determined by colum chromatography, and the normal value was less than or equal to 7 percent. One hundred and fifty NIDDM patients were examined during the period of 15 months, and 91 patients fullfil the criteria of good controled diabetic (HbA1 less than or equal to 7 percent). From this 91 patients, only 28 patients (30.8 percent) showed normal serum lipids. Among the 63 dyslipidemic patients (40.6 percent) had hypercholesterolemia only, 4 (4.4 percent) had hypertriglycerdemia, 12 (13 percent) had hypercholesterolemia as well as hypertriglyceridemia, mostly hupercholesterolemia and hyperchlesterolemia plus hypertriglyceridemia. From this study it can be concluded that even in good controlled NIDDM patients, significant number of patients are still dyslipidemic. These data indicate that significant number of good controlled NIDDM patients may need a hypolipidemic agent to reach a normal lipid profiles.

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Medika,22(10)1996:779-782

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: ., 1996

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lipids
diabetes mellitus, non-insulin-dependent

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