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Great progress in molecular biology and medicine has made it possible to develop a novel, more selective chemotherapy based on signal-transduction principles. Signal-transduction pathways are identified by the cell as a device for the control of metabolism and proliferation. The transformation of a normal cell to a cancer cell is a complex multistep process. It is clear that hyperproliferation …
Balloon Mitral Valvuloplasty (BMV) has become established as a non surgical alternative for the treatment of mitral stenosis. Although most patients benefit immediately from this procedure, results in individual patients are variable. Therefore, the purpose of this study was to detect the prediator factors of succesessful outcome in 228 mitral stenosis patients who underwent BMV at Cardiac Cent…
Following the WHO-MONICA protocol, in 1988 a community survey of Coronary Heart Disease (CHD) has been done in 3 sub-districts of metropolitan Jakarta, after 5 years intervention in the form of health education in CHD-risk factors control, a second survey has been completed in 1993. Comparison of results of the first and the second surveys. nl. prevalence of hipertension (14.9 percent vs 49.6 p…
The goal of nutritional support is to maintain or replete lean body mass, to support host defense mechanisms, to avoid specific nutritional deficiencies, and in general to improve clinical outocome in a malnourished patient or in at risk to develop malnourishment. Nutritional support can be instituted by enteral or parenteral route; each has its advantages and disadvantages. Which mode of deliv…
Cranial ultrasound examination was performed on 91 low birth weight infants to determine the occurence of cerebral hemorrhage with or without ventriculomegaly. In very low birth weight infants cerebral hermorrhage was found in 35 percent, while the hemorrhage plus ventriculomegaly was found in 18 percent of the infants. In all low birth weight infants cerebral hemorrhage was found in 17 percent…