The aim of this research is to obtaine a sustained release dosage form with cellulose derivatives by microencapsulation method. In this study, the microencapsulation method modified from Lordi, by spraying the ethanolic solution of methylcellulose, ethylcellulose and hydroxyprapyl methylcellulose. Particles of the active substance were put in the coating pan and sprayed carefully with the solut…
Anthistamines such as CTM, diphenhydramine HCI, promethazine HCI and astemizol have different physicochemical properties due to the differences in their chemical structures. These physicochemical properties would affect their transport behavior through cellophane membrane. This study would like to investigate the effect of physicochemical properties of the antihistamines on their transport thro…
The effectiveness of sun screen depends on the stability of drug used as an active compound, and its influence on the chemical components in skin cell. To study of the effectiveness of octylmethoxycinamate (OMC) as sun screen, the phostostability of OMC was examined by exposing the compound with direct sunlight. The influence of OMC on the stability of tryptophan was also studied. The layer was…
A cross secttional study of household contacts of leprosy patients had been done in Pare-pare Regency during July to September 1994. The objective of this study is to know the correlation of age, sex, duration of contact and type of leprosy as the source of household contact to the result of serologic and lepromin tests and the correlation between the lepromin test and serologic test in househo…
A follow-up study was conducted at Renal Unit Sardjito Hospital Yogyakarta Indonesia, between November 1992 and November 1994 to determine the role of hemodialysis duration on the evolution of lipid profile in chronic renal failure patients with hemodialysis. Considering abnormal levels of HDL-cholesterol of less than 45 mg/dl and Apo-A1 less than 165mg/dl, at baseline, we found abnormal mean H…
A study has been conducted on the use of by product of coconut pulp as a source of mannitol by reducing and hydrolizing this by product. The purpose of the study was to choose the proper hydrolizing agent in order to obtain a maximum product. It was found that the proper substance to hydrolize the coconut by product was 1 N hydrochloric acid, with a preliminary treatment in four hours. The hydr…