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Two cases of pemphigus foliaceus in a 31-years old man and a 33-years old woman, treated in the outpatient department of the Department of Dermato-venereology Palembang General Hospital, are reported. The cases were initially diagnosed as seborrhoic dermatitis and discoid lupus erythematosus as the lesions were located on the face and there were no obvious blisters. The disease is a rare entity…
Treatment is an important aspect of leprosy control. Effective chemotherapy not only cures the patients, but also disrupts the transmission of infection. Development of chemotherapy of leprosy can be divided into three eras : presulfon, sulfon monotherapy, and multidrug therapy (MDT) era. This paper reviews the development of leprosy chemotherapy and drugs used in MDT : dapson, rifampisin, clof…
The workers of automobile assembling industry consists of painters, welders, assemblers and mechanic workers, are exposed to several sensitizers such as chrome, nickel, cobalt, epoxy and acrylic resin, glue and rubber. Also, several irritants such as solvents, oil, cutting oil, and cleaners. The most common occupational skin disease that occured among those workers are fiberglass dermatitis, so…
Osteomyelitis is a bacterial infection of the bone and the bone marrow. The disease may occur as a result of direct invasion through a penetrating wound or an open fracture, but hematogenous spread of infection from other infected areas is more common. Staphylococcus aureus is the most common infecting organism. Acute hematogenous osteomyelitis is primary a disease of growing bones and, therefo…
Several theories on the pathogenesis of atherosclerosis may be integrated into a single multifactorial one. According to this theory, the most probable sequence of events involved in early atherosclerosis is a vascular dysfunction or injury, monocyte and macrofage recruitment, lipid deposition, synthesis of extracellular matrix. The interaction of all these factors will create the characteristi…
GnRH is a decapepride that is synthesized in the cell bodies of the hypothalamic neurons and secreted directly into the hypophysioportal circulation. On arrival at the anterior potuitary gland, GnRh selectively stimulates the gonadotrophin cells to release the LH and FSH. Both hormones regulate and maintain the function of spermatogenesis. Treatment with GnRH agonists or antagonists are able to…