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Accurate information about drug use in the community has three main applications. Firstly, audits of prescribing patterns can be conducted, perhaps to assess their appropriateness. Secondly, the data can be used to monitor cost associated with drug therapy. Thirdly, drug usage data can be used to investigate problems related to drug safety. According to WHO (1973), drug utilization was defined …
Paracetamol has been widely used against fever and acts as an analgesic. This drug, however, could be hepatotoxic and nephrotoxic. Many hepatoprotector drugs have been used to prevent against liver damage, through they showed no convincing results. (+) Cyanidanol-3 was reported to be able to prevent the permeability of liver cell membrane. This experiment was design to study the role of (+) Cya…
Retinoid is a common name for natural or synthetic vitamin A with or without a biologic activity of retinol. During the past several years it was reported that retinoid can prevent or inhibit the malignant growth of tumor cells. Although not completely known, it was also reported that retinoid can reverse the effets of carcinogens in vivo. It was thought that its inhibitive effects on tumor cel…
Urinary calculi has been known long before the era of Hippocrates; and at the beginning of this century, stones in the urinary bladder is reportedly more frequent than those in the kidney or in the ureter. The structure of the urinary calculi is rather complex. Stones will be formed when concentration of some metabolites increases and exceeds its solubility level. However, if the urine output i…
A physical fitness test using Harvard technique has been made for the male Medical Faculty student, Trisakti University 1992/1993 period. From the 50 healthy selected male candidates only 2 responding as 'EXCELLENT' 7 as 'GOOD' and the other 41 as 'FAIR'. Personal motivation of candidates highly determines the result of the test. Feeling easily tired and feeling afraid could made them stop the …
Metastrongylid nematodes of the genus Angiostrongylus have been found to be important human parasites. Angiostrongylus cantonensis, a lungworm that lives in the pulmonary artery of rats is a cause of human eosinophilic meningitis in many Pacific islands including Hawaii, Thailand, Indonesia and other parts of Southeast Asia and in Cuba. In the life cycle, rats excrete first-stage larvae in fece…
Ascaris lumbricoides is found in 50-100 percent of population in Indonesia especially in suburb areas. The male worm has 15-31 cm length with curly tail, whereas the female is about 20-35 cm and produces around 200,000 eggs per day, with size 60x45 micron. The best environment for the eggs is though soil (clay) with temperature between 25-300 degree C. Since the adult worms take nutrients from …
Chrom is a trace element which was originally found by Schwarz and Mertz in 1959 as an essential mineral to animals. Later, it was also found that the deficiency of this element in human caused a variety of symptoms, especially in persons or patients who had a long term of parenteral diet. Chrom deficiency in human as well as in animal is recognized by patients intolerance to glucose, and the i…