The present work was aimed to compare the pharmacokinetic profiles of sulfanilamide and its derivative sulfamethizole in the rat. Female Wistar rats were divided into two equal groups randomly, and each was injected with sulfanilamide or sulfamethizole (40 mg/kg: ip). The sulfonamide blood concentrations were monitored colorimetrically employing a Bratton-Marshall assay method. The result showe…
An investigation has been performed to monitor cephalexin in blood, urine and feces of rats following administration of its derivative N-benzoyl-cephalexin. Female Wistar rats were randomly divided into two groups of six animals. To the first group N-benzoyl cephalexin (equivalent to cephalexin 25 mg/kg) was given orally in 10 percent PVP suspension to the fasted rats. Blood samples (200 ul) we…
It is essential to weight the baby accurately at birth so that apropriate measures can be taken to minimize the risk. In rural areas, most deliveries occur at home, attended by traditional birth attendants and there is a shortage of weighing scales. Therefore, suitable surrogates for birth weight are needed. A prospective study was conducted to assess the diagnostic performance of four anthropo…
A case control study was carried out in Sardjito General Hospital Yogyakarta to evaluate the risk factors for gestational trophoblactic diseases. One hundred and seven cases of trophoblas diseases fulfiling the inclusion criteria were included in this study. Data were obtained from the hospital medical record, and every case was conducted by 2 controls (normal delivery). It was found that woman…