Ranitidine HCI is an H-2 receptor antagonista for the treatment of peptic gastric secretion with small biovailability, so that should be developed in a sustained release dosage form are retained in the stomach. Ranitidine HCl floating tablet was formulation by effervescent system. Simplex lattice design was applied to optimize the formula of ranitidine HCl floating tablet by varying levels of …
Parotid pleomorphic adenoma (PPA) is a benign turnor frequently found in parotid salivary gland. This tumor has various biological behaviors including recurrence after surgery, ability to transform into the malignant form, and occasionally, metastasizes to lymph nodes or other organs. For this PPA turnor, it is appropriate to look for alternative therapy forms other than surgery which is assume…
Isolation method to obtain pure BMVECs is hard to be done consistently and remains a challenge. In this study, we isolated BMVECs from Wistar rat and C571B16 mouse from Japan SLC. All procedures performed according to guidelines for the care and use of laboratory animals of Gunma University, Japan. The modification of isolation method was using bovine serum albumin (BSA) gradation, not Dextran-…
The effect of eurycoma longifolia and pimpinella alpina on spermatogenesis in male Spraoue Dawly Background: Alternative medicine used to overcome infertility among others is using traditional herbs. Crops which often used are pasak bumi (Eurycoma longifolia) and purwaceng (Pimpinella alpina). Several studies reported that pasak bumi and purwaceng could improve testosterone, luteinizing hormon…
Steroid resistant n~protic syndrome are patients who showed no remission after standard therapy of steroid. Until now, steroid resistant mechanism occurs through two ways, that are non gene that related with immunologic based and gene related with primary defect on glomerular filtration barrier. This paper describes those genes known related to the pathogenesis of steroid resistant nephrotic sy…
Captopril has only 6-8 h duration of antihypertensive action, most stable at acidic condition and as the pH increased, it becomes unstable and undergoes a degradation reaction.These facts indicate a promising potential of the captopril floating system as an alternative to the conventional dosage form.The objective of the recent investigation was to find an optimum formula of floating tablet for…
The novel compounds of 2-hydroxynicotinyl octylamide (NOA) were synthesized by modifying of the UK-3A compound known biologically active to inhibit bacterial and cancer cell growth. Synthesis of 2-hydroxynicotinyl octylamide (NOA) were carried out in one step reaction for the second compound. NOA was synthesized by amidation reaction between 2-hydroxynicotinic acid and octylamin yielded 76.1% o…
The objective of the research was to study the effect of reducing feedstuff and water stressor on the level of antibody, percentage of Iymphocytes, macrophage and the leukocytes values in facing the stressor. The research used 180 medium type chickens, strain Oekalb Warren, aged 84 weeks old. The research applied 2x2x2 factors and used complete randomized design in 5 times replications with 4 c…