The aim of this research is to obtaine a sustained release dosage form with cellulose derivatives by microencapsulation method. In this study, the microencapsulation method modified from Lordi, by spraying the ethanolic solution of methylcellulose, ethylcellulose and hydroxyprapyl methylcellulose. Particles of the active substance were put in the coating pan and sprayed carefully with the solut…
The aims of this study were to find out formulas of granules made from complexes drugs-shellac resin that has constant release pattern. The influence of pH on the drugs release was also investigated. The drug-shellac resin complex was made by dispersing disclofenac sodium into alcoholic solution of shellac. Three different ratios of the drug-shellac resin (1:5; 1:3; 1:1) respectively were made.…
The aim of this research is to obtaine a sustained release dosage form with cellulose derivatives by microencapsulation method. In this study, the microencapsulation method modified from Lordi, by spraying the ethanolic solution of methylcellulose, ethylcellulose and hydroxyprapyl methylcellulose. Particles of the active substance were put in the coating pan and sprayed carefully with the solut…