Background: Low plasma total glutathione (tGSH) levels, elevated levels of oxidized glutathione (GSSG) and low ratios of tGSH to GSSG in autism were reported. Glutathione S-transferases (GST) are antioxidant enzymes that play important role in cellular detoxification and the excretion of environmental pollutants including heavy metals. Glutathione S-transferase mu (GSTM1) and Glutathione S-tran…
SHOX gene is located on the edge of each short/p arm sex chromosome called the pseudoautosomal region-1 (PARI) plays as a dindomental role on controling chondrocyte differentation and apoptosis in the growth plate. Longitudinal growth is determined by environmental, hormonal and genetic factors. Short stature is defiened as a stature is defined as a standing height below the third percentile ac…