The present work was aimed to compare the pharmacokinetic profiles of sulfanilamide and its derivative sulfamethizole in the rat. Female Wistar rats were divided into two equal groups randomly, and each was injected with sulfanilamide or sulfamethizole (40 mg/kg: ip). The sulfonamide blood concentrations were monitored colorimetrically employing a Bratton-Marshall assay method. The result showe…