BACKGROUND Doxorubicin as an ant icancer drug has hepatotoxic side effects. Curcuma xanthorrhiza. Curcuma longa and Zingiber officinale are commnonly used as herbals in lndonesia and around the world. Several compounds in these plants have antiox idant activities and are known to exhibit protection against doxorubicin-induced toxicities. This study aimed to observe the hepatoprotective effect…