Human papiloma virus (HPV) is the most common cause of sexually transmitted infection worldwide. Condyloma acuminata is the most common form of HPV infection. In HIV patient, the risk to get multiple HPV infection is increased, while in man who have sex with man (MSM), the risk to develop into malignancy is even geater. A case of condyloma acuminata (CA) in the anal region caused by HPV type 6,…