ABSTRACT Background: Rapid and accurate information on susceptibility of bacteria causing bacteraemia is very helpful in sepsis management. Blood culture is the gold standard for bacteraemia diagnosis. Standard antibiotic susceptibility testing needs at least three days for completion while direct method can give the result a day earlier The aim of this study was to investigate the diagnostic …
Tug boat is the transportasion equipment in the sea that can be used to conduct many of job that like to drag, postpone, pool, and anchor the ship and other floating equipment. Usually to the water for the ship supply taken from the closest place to the port and so save the water put in the tank that made from the steel. In is possible occur the pollution of metal element especially timbale. Ti…
MnSOD and catalase are endogeneous antioksidants which function to neutralize five radicals. Oxydative stress causes oxidative damage which can be measured by elevated levels of Malondialdehyde (MDA) in the cells. Chronic systemic hypoxia is a condition caused by a systemic decrease in oxygen intake in the long term. This condition can cause oxidative stress that result in oxidative damage to c…
Background: Exercise increases the need for oxygen to generateATP through oxidative phosphorylation. If the high energy demand during exercise is not balanced by sufficient oxygen supply, hypoxia occurs in skeletal muscle tissue leading to upregulation ofhypoxia inducible factor-1α (RIF-1α). The activity of RIF-1α increases the expression ofvarious genes in order to reduce the metabolic depe…
Background: Cobalt chloride can be used as an agent to stabilize hypoxia inducible factor-1α (HIF-1α) and to imitate hypoxia without low levels of oxygen inside the body. We intended to Investigate if there was any regulation of renin expression by HIF -1α. Therefore, we conducted several studies to elarify this possibility starting with the induction of hypoxic mimicry in rats by intra-per…
Background: The goal of this study was to analyze the correlation of oxidative stress in human glioma cells with tumor grade in order to explore the role of oxidative stress as a marker in determining the tumor progression. Methods: Samples were 21 brain tumors and 5 normal brain tissues from glioma patients. Oxidative stress was analyzed by measuring malondialdehyde (MDA), carbonyl and 8-hyd…
Stability of erythropoietin (EPO) depends on its glycosylation states. With more glycosylation sites, the EPO protein will be more stable and also increase its half-life. A construct of recombinant human erythropoietin (rhEPO) which contains 2 additional N-link for glycosylation were designed. Based on translation analysis using ORF (open reading frame)-finder and protein alignment analysis usi…