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Interest in amorphous pharmaceutical systems is steadily growing over the last 10 years. The amorphous state is critical in determining the solid state, physical and chemical properties of many pharmaceutical dosage forms. The main reason of the growing interest toward amorphous materials is the need to improve the bioavailability of drugs with poor aqueous solubility. Many drugs exist in cryst…
Zinecard is used to prevent a toxic effect to heart caused by certain medicines that are used to treat cancer. Zinecard is also used to treat tissue damage caused by the leakage of certain medicines that are used to treat cancer. Differential pulse polarographic method developed for the quantitative determination of zinecard gives a peak at -0.32 V at DME. From the structural point of view zine…
Psidium guajava L. (Myrtaceae) is a well known plant in Malaysia and Indonesia. Its leaves extract was found to possess antidiarrhea, antimicrobial, hepatoprotective and antioxidant activities. Objective of this research is to isolate an antioxidant subtance from Red Psidium guajava L. leaves. The crude leaves was extracted using Soxhlet apparatus by gradual polarity of three different solvents…
Using of curcumin as anti cancer agent is restricted by its low solubility, therefore it has low bioavability. This obstacle can be solved by the development of curcumin nanoparticle. Nanoparticle technology has been started to be developed as an alternative solution to improve drug delivery pofile, especially for the less bio-available chemical. This study was aimed to develope nanocurcumin fo…
Objective: To compare the effectiveness after administration of Renalof® to Kalkurenal ® and placebo in patient with renal calculus. Material & Method: We analyzed 30 patient with renal calculi less than or equal to 20 mm (2 cm) between January 2011 and March 2011. Patients were divided into 3 groups. Nine patients were treated with placebo, 8 patients were treated with Kalkurenal® and the l…
This is a pre survey according to handle of “outbreak” in Grujugan’s village Central Java, with crossectional study to take quantitative data. Secunder datas were taken from Health District Office in Banyumas, Central Java. Focus group discussion of qualitative study was taken from head of village Grujugan dan head of Primary Health Care of Kemranjen II, and in depth interview to two pa…