The novel compounds of 2-hydroxynicotinyl octylamide (NOA) were synthesized by modifying of the UK-3A compound known biologically active to inhibit bacterial and cancer cell growth. Synthesis of 2-hydroxynicotinyl octylamide (NOA) were carried out in one step reaction for the second compound. NOA was synthesized by amidation reaction between 2-hydroxynicotinic acid and octylamin yielded 76.1% o…