Cyclooxygenase-2 (COX-2) expression and selective COX-2 inhibitor such as celecoxib, which widely used as antiinflamatory drug, is known to have role in cancer by reducing proliferation and growth of turnor cells, and increasing apoptosis. The research aims were to investigate the effect of selective COX-2 inhibitor and role of COX- 2 on tumor growth. This was an experimental study with pretest…