Metformin hydrochloride is an orally administered biguanide derivative drug and functions as an anti hyperglycemic in patient with type 2 diabetes mellitus with bioavailability between 50-60%. Floating system is the one method to enhance absorption and bioavailability of metformin hydrochloride. The purpose of this research was to determine the effect of guar gum concentration and concentration…
Ibuproten is an antiinflamatory drugs with poor solubility in water but good permeability in the gastrointestinal tract. Liquisolid tablet is the one method of increasing solubility and dissolution rate of ibuproten. The aims of this study was to determie the effect of glycerine and proprotein. The aims of this study was to determine the effect of gilcerine and propylene glicol as non volatile…
Ibuprofen is an anti-inflammatory drug and is practically insoluble in water. The low melting point and the por flowability of ibuprofen can lead to process difficulty in tablets production. The purpose of this research was to make the sodium salt from of ibuprofen which has better solubility in water. Sodium ibuprofen salt was prepared by reacting the ibuprofen and sodium hydroxide, then chara…