Annona muricata Linn. or soursop containts acetogenin which can induce apoptotic in in vitro assay and has cytotoxic effect. The study has been done to examine the soursop leaves extract's potency in in vivo assay to suppress tumor development by 7,12- dimethylbenz[a]anthracene (DMBA) induced. The induction process has been done twice a week for five weeks to white rat, Sprague Dawley’s s…