ABSTRACT BACKGROUND Hypertension is associated with endothelial-dependent vasodilation disorders, due to reduced nitric oxide (NO) availability and excessive angiotensin II (ANG¬II) activation. The objective of this study was to determine the association between matrix metallopeptidase 9 (MMP-9) gene polymorphism and hypertension in ethnic Javanese in the 40-80 year age group. METHODS…
Aksis hipotalamus-hipofisis-testis (HHT) sudah diketahui diatur oleh gonadotropin releasing hormone (GnRH) dan mekanisme umpan batik melalui testosteron dan inhibin. Penemuan adanya neuropeptida hipotalamus baru sebagai faktor penghambat pengeluaran gonadotropin, gonadotropin inhibiting hormone (GnIH) menimbulkan perubahan baru dalam aksis HHT. Ekspresi GnlH pada otak nukleus paraventrikuler (P…