ABSTRACT Elevated Intracranial pressure (ICP)due to hydrocephalus (HCP)causes some thinning in cerebral mantle and increasing of Evan's ratio (ER). Apoptosis and neuronal degeneration play an important role in this pathological change. The Evan's ratio improvement after Ventrikulo-Peritonea! Shunt (V-P Shunt) insertion in congenital hydrocephalus is uncertain, Brain Derived Neurotropic Fac…