Obstruction of the urinary tract has marked effects on renal blood flow glomerular filtration rate (GFR). And tubular function. Ureteral obstruction results in an injury response that can progress to irreversible renal fibrosisand tubular damage by apoptosis. Forty five rabbits aged 13-17 weeks with body weights of 1250-1750 grams were devided into 4 groups. Group 1 underwent a sham operation a…