Antinobacillus actinomycetemcomitans serotype b has long been associated with localized aggresive poriodontitis secreted protein toxin that inhibits the proliteration of wide variety of cell typesEucariotic cells that are sensitive to the toxin are usually arrested at the GO/GI or G2/M phase ofthe growth cycle through the action of a DNA-se 1-like nuclese that causes double stand breaks in the …