Background: This study was done to determine the effect of root extract of Acalypha indica Linn (akar kucing) in protecting neuron viability ofthe rat hippocampus on tissue culture in hypoxic condition. Methods: This is an experimental study of in vitro prirnary cell culture of hippocampus of Sprague Dowley aduh rat. The cultures were group into control (C) and exposure to root extract of Aca…