Ovarian aging has been noted in some vertebrate animals and human being, indicated by low estrogen level. This is related to enhancement of lipid (obesity) and some metabolic diseases such as hyperlipidemia, cardiovascular disease, etc. Pare juice (Momordica charantia L.), contains of abundant advantageous bioactivities, such as hypoglycemic effect, antioxidant, hypocholesterolemic, and hypo…