Stability of erythropoietin (EPO) depends on its glycosylation states. With more glycosylation sites, the EPO protein will be more stable and also increase its half-life. A construct of recombinant human erythropoietin (rhEPO) which contains 2 additional N-link for glycosylation were designed. Based on translation analysis using ORF (open reading frame)-finder and protein alignment analysis usi…
Obstruction of the urinary tract has marked effects on renal blood flow glomerular filtration rate (GFR). And tubular function. Ureteral obstruction results in an injury response that can progress to irreversible renal fibrosisand tubular damage by apoptosis. Forty five rabbits aged 13-17 weeks with body weights of 1250-1750 grams were devided into 4 groups. Group 1 underwent a sham operation a…
To study the rate of urethrocutaneous fistule formation associated with the use of an indwelling catheter with stent hypospadias repair. Twenty patients with primary hypospadias of penile shaft and posterior type underwent reconstruction with an onlay technique by a single operator. For urinary deviation in 10 patients a urethral catheter was used, while in the remainder a silicone suprapublic …
LUTS is a syndrome of BOO which marked by obstructive and irritable symptoms. The ball valve mechanism in bladder neck results in an increase of bladder outlet obstruction (BOO). The aim of this study is to prove the relation of intravesical prostatic protruson (IPP) with prostate volume, Q max, and international prostate symptom score (IPSS) in non complicated BPHLUTUS patients. This study is…